Pafos FC began their European campaign on July 23, 2026, with a 2-0 away defeat against Hajduk Split in Croatia during the first leg of the UEFA Europa League second qualifying round. Played at the Poljud Stadium, the match remained scoreless until the 56th minute, when Sego broke the deadlock with a direct free kick that hit the crossbar before entering the net. Hajduk Split doubled their lead in the 65th minute through a goal by Melnjak, finalizing the result.

Manager Ricardo Sa Pinto acknowledged that his team struggled with clinical finishing, despite creating opportunities. He highlighted that while the result felt unfair given the team's performance—specifically praising the contributions of Zaza—the lack of precision proved costly. This match marked the first official European test for Pafos FC this season, following a preparation period that included a friendly against Slovan Bratislava.

The two clubs are now set for the return leg, which will take place next week at the Alphamega Stadium in Limassol. Pafos FC must overturn the two-goal deficit on home soil to keep their hopes of advancing in the competition alive.